BiophysicsbioRxiv
Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides
A. L. B. Pyne, A. Noy, K. Main…·S. A. Harris
This study uses AFM and MD simulations to analyze how DNA supercoiling affects structure and triplex-forming oligonucleotide binding at base-pair resolution.
DOI 10.1038/s41467-021-21243-y