Exploiting cryo-EM structures of actomyosin-5a to reveal the physical properties of its lever
M. S. C. Gravett, D. P. Klebl, O. G. Harlen…·M. Peckham
This study uses cryo-EM and molecular dynamics to determine the structure and physical properties of Myo5a's lever, revealing its working stroke and implications for its walking mechanism.