Cancer BiologyCell Death & DifferentiationPeer-reviewed
Thymidylate synthase maintains the de-differentiated state of aggressive breast cancers
A. Siddiqui, P. N. Gollavilli, A. Schwab…·P. Ceppi
This study shows that thymidylate synthase promotes de-differentiation in aggressive breast cancers by supporting pyrimidine catabolism and EMT, correlating with poor prognosis.
DOI 10.1038/s41418-019-0289-6