MicrobiologybioRxiv
The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir
T. Dinh, Z. Tber, J. S. Rey…·M. Kvaratskhelia
This paper identifies the mechanism of resistance to the HIV-1 integrase inhibitor pirmitegravir and develops a more potent analog to overcome this resistance.
DOI 10.1128/mbio.00465-24