Author

F. Amblard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

R. F. Schinazi· 3 shared A. B. Evans· 1 shared A. Conde· 1 shared A. S. Annamalai· 1 shared B. Kim· 1 shared C. Delevoye· 1 shared C. Manfredi· 1 shared C. S. Hill· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

R. F. Schinazi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir

T. Dinh, Z. Tber, J. S. Rey, S. Mengshetti, A. S. Annamalai, R. Haney, L. Briganti, F. Amblard, J. R. Fuchs, P. Cherepanov, K. Kim, R. F. Schinazi, J. R. Perilla, B. Kim, M. Kvaratskhelia

This paper identifies the mechanism of resistance to the HIV-1 integrase inhibitor pirmitegravir and develops a more potent analog to overcome this resistance.

bioRxiv · Jan 26, 2024Microbiology

Development of robust antiviral assays using relevant apical-out human airway organoids

J.-H. Lee, J. C. LeCher, E. Parigoris, N. Shinagawa, J. Sentosa, C. Manfredi, S. L. Goh, R. De, S. Tao, K. Zandi, F. Amblard, E. J. Sorscher, J. R. Spence, R. Tirouvanziam, R. F. Schinazi, S. Takayama

This paper develops AORBs, a high-throughput human airway organoid system, to robustly assess antiviral efficacy against SARS-CoV-2 with high throughput and clinical relevance.

bioRxiv · Jan 2, 2024 · PreprintBioengineering

N4-Hydroxycytidine/Molnupiravir Inhibits RNA-Virus Induced Encephalitis by Producing Mutated Viruses with Reduced Fitness

D. Ojha, C. S. Hill, S. Zhou, A. B. Evans, J. M. Leung, C. S. Lewis, F. Amblard, R. F. Schinazi, R. S. Baric, K. E. Peterson, R. Swanstrom

This study shows that N4-hydroxycytidine and its prodrug molnupiravir reduce RNA-virus-induced encephalitis by producing less fit viruses with G-to-A and C-to-U mutations.

bioRxiv · Aug 22, 2023 · PreprintMicrobiology

Dynlt3, a novel fundamental regulator of melanosome movement, distribution, maturation and transfer

Z. Aktary, A. Conde, F. Rambow, M. Di Marco, F. Amblard, I. Hurbain, G. Raposo, C. Delevoye, S. Coscoy, L. LARUE

This study identifies Dynlt3 as a critical regulator of melanosome transport, maturation, and transfer in melanocytes, revealing its role in skin pigmentation through interactions with the Wnt/β-catenin pathway.

bioRxiv · Jan 13, 2021 · PreprintCell Biology