Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
N. E. Sapp, N. Burge, K. Cox…·C. Dash
This study identifies that HIV-1 preintegration complex preferentially integrates viral DNA into nucleosomes with H3K36me3 modification and linker DNA.
C. Shema Mugisha, T. Dinh, A. Kumar…·S. Kutluay
This study identifies compensatory mutations that restore HIV-1 integrase-gRNA binding and infectivity, revealing the role of electrostatic interactions in this process and their impact on allosteric inhibitor sensitivity.
N. Deng, C. Tse, L. Wickstrom…·R. Levy
This paper investigates the thermodynamics and free energy landscape of HIV-1 integrase multimerization induced by an allosteric inhibitor, revealing short-range interactions and enthalpy-driven binding.
J. Elliott, J. E. Eschbach, P. C. Koneru…·S. B. Kutluay
This study identifies three mechanisms by which class II HIV-1 integrase substitutions disrupt IN-RNA interactions, leading to virion maturation defects and premature viral genome degradation.
W. Lu, N. Tirumuru, P. C. Koneru…·L. Wu
This study shows YTHDF1-3 proteins inhibit HIV-1 infection by binding m6A-modified viral RNA, reducing reverse transcription and viral production.