Author

L. C. Garner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

M. E. B. FitzPatrick· 3 shared N. M. Provine· 3 shared P. Klenerman· 3 shared A. Amini· 2 shared C. Pearson· 1 shared C.-P. Hackstein· 1 shared D. Costigan· 1 shared E. E. Thornton· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersImmunology

M. E. B. FitzPatrick

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Author profile →

3 papers

Recent·Most cited

A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice

C.-P. Hackstein, D. Costigan, L. Drexhage, C. Pearson, S. Bullers, N. Ilott, H. D. Akther, Y. Gu, M. E. B. FitzPatrick, O. J. Harrison, L. C. Garner, E. H. Mann, S. Pandey, M. Friedrich, N. M. Provine, , E. E. Thornton

The paper identifies a conserved population of MHC-II restricted, innate-like T cells in the gut of humans and mice that react to commensals and are implicated in colitis.

bioRxiv · Sep 26, 2022 · PreprintImmunology

Human MAIT cells show clonal diversity but transcriptional and functional homogeneity

L. C. Garner, A. Amini, M. E. B. FitzPatrick, N. M. Provine, P. Klenerman

The paper analyzes MAIT cell clonal diversity and functional responses using single-cell RNA-seq and fRNA-seq, finding high TCR diversity and tissue-specific functional patterns.

bioRxiv · Feb 26, 2022Immunology

Human intestinal tissue-resident memory CD8+ T cells comprise transcriptionally and functionally distinct subsets

M. E. B. FitzPatrick, N. M. Provine, L. C. Garner, K. Powell, A. Amini, S. Irwin, H. Ferry, T. Ambrose, P. Friend, G. Vrakas, S. Reddy, E. J. Soilleux, P. Klenerman, P. J. Allan

This study identifies transcriptionally and functionally distinct subsets of human intestinal TRM cells, with β2-integrin marking a unique CD8+ TRM population.

bioRxiv · Dec 11, 2019Immunology