K. Powell

Intrinsic diving reflex induces potent antioxidative response by activation of NRF2 signaling

This study shows that both acute and chronic diving reflex activate NRF2 signaling, with acute exposure inducing stronger antioxidative gene expression than chronic exposure.

Primed to resolve: A single cell atlas of the shoulder capsule reveals a cellular basis for resolving inflammatory fibrosis

This study identifies MERTK+ macrophages and fibroblasts involved in resolving fibrosis in frozen shoulder using single-cell analysis and suggests therapeutic strategies to enhance their interaction.

Complex multiple introductions drive fall armyworm invasions into Asia and Australia

The paper uses population genomic analysis to trace multiple introductions of fall armyworm into Asia and Australia, showing human-assisted spread via trade and identifying genetic melting pot dynamics.

An efficient and robust HPLC method to determine the sialylation levels of human epithelial cells

This paper develops an HPLC-UV method to quantify sialic acids in cancer cells, showing it is efficient and effective for assessing sialyltransferase inhibitor efficacy.

An Orally Available Cathepsin L Inhibitor Protects Lungs Against SARS-CoV-2-Induced Diffuse Alveolar Damage in African Green Monkeys

This study shows that the orally available cathepsin L inhibitor K777 reduces SARS-CoV-2-induced lung damage in African green monkeys.

Human intestinal tissue-resident memory CD8+ T cells comprise transcriptionally and functionally distinct subsets

This study identifies transcriptionally and functionally distinct subsets of human intestinal TRM cells, with β2-integrin marking a unique CD8+ TRM population.