Author

C.-P. Hackstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

P. Klenerman· 3 shared E. Marchi· 2 shared F. Powrie· 2 shared M. Friedrich· 2 shared A. Bhalla· 1 shared A. J. Carr· 1 shared A. Lee· 1 shared C. C. Machado· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

P. Klenerman

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3 papers

Recent·Most cited

Primed to resolve: A single cell atlas of the shoulder capsule reveals a cellular basis for resolving inflammatory fibrosis

M. T. Ng, R. Borst, H. Gacaferi, S. Davidson, C. C. Machado, I. Reekie, M. Attar, D. Windell, M. Kurowska-Stolarska, L. MacDonald, S. Alivernini, M. Garvilles, K. Jansen, A. Bhalla, A. Lee, , S. G. Dakin

This study identifies MERTK+ macrophages and fibroblasts involved in resolving fibrosis in frozen shoulder using single-cell analysis and suggests therapeutic strategies to enhance their interaction.

bioRxiv · Jan 16, 2023 · PreprintCell Biology

A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice

C.-P. Hackstein, D. Costigan, L. Drexhage, C. Pearson, S. Bullers, N. Ilott, H. D. Akther, Y. Gu, M. E. B. FitzPatrick, O. J. Harrison, L. C. Garner, E. H. Mann, S. Pandey, M. Friedrich, N. M. Provine, , E. E. Thornton

The paper identifies a conserved population of MHC-II restricted, innate-like T cells in the gut of humans and mice that react to commensals and are implicated in colitis.

bioRxiv · Sep 26, 2022 · PreprintImmunology

TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions

T. Leng, H. Delowar Akther, C.-P. Hackstein, T. King, M. Friedrich, Z. Christoforidou, S. McCuaig, M. Neyazi, C. V. Arancibia-Carcamo, F. Powrie, Oxford IBD Investigators, E. Marchi, R. Sanchesperes, V. Millar, D. Ebner, , P. Klenerman

This study investigates how TCR and inflammatory signals shape human MAIT cell functions, revealing their roles in tissue repair and effector responses.

bioRxiv · May 14, 2019Immunology