Author

L. Cen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

W. Shi· 3 shared X. He· 3 shared J. S. McLean· 2 shared P.-T. Dong· 2 shared A. Bag· 1 shared A. Schultz· 1 shared B. Batbileg· 1 shared B. Bor· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersMicrobiology

W. Shi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Episymbiotic bacterium induces intracellular lipid droplet production in its host bacteria

P.-T. Dong, J. Tian, K. J. Kobayashi-Kirschvink, L. Cen, J. S. McLean, B. Bor, W. Shi, X. He

This study investigates the interaction between Saccharibacteria TM7x and its host XH001, revealing TM7x-induced lipid droplet formation in XH001 and its protective role under stress.

bioRxiv · Sep 6, 2023 · PreprintMicrobiology

Targeting Fusobacterium nucleatum through Chemical Modifications of Host-Derived Transfer RNA Fragments

M. Yang, P.-T. Dong, L. Cen, W. Shi, X. He, J. Li

The paper chemically modifies host-derived tRNA fragments to selectively inhibit Fusobacterium nucleatum with nanomolar efficacy, while sparing other oral bacteria.

bioRxiv · Sep 29, 2022Bioengineering

Transcriptome of epibiont Saccharibacteria Nanosynbacter lyticus strain TM7x during establishment of symbiosis

E. L. Hendrickson, B. Batbileg, K. A. Kristopher, E. I. Lamont, L. Cen, Y. Chang, J. Liu, W. Shi, X. He, J. S. McLean

This study examines gene expression changes in Saccharibacteria TM7x and its host during symbiosis establishment, revealing dynamic interactions and functional roles in maintaining the relationship.

bioRxiv · Mar 25, 2022Microbiology

The immunomodulatory properties of the HDAC6 inhibitor ACY241 supports robust anti-tumor response in NSCLC when coupled with the chemotherapy drug Oxaliplatin

A. Bag, A. Schultz, S. Bhimani, W. Dominguez, L. Cen, D. Adeegbe

This study shows that ACY241, an HDAC6 inhibitor, enhances anti-tumor responses in NSCLC when combined with Oxaliplatin by modulating tumor immune cells.

bioRxiv · Oct 1, 2021 · PreprintImmunology