Author

L. Dalen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 9

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 6 Approach:statistical model· 5 Research Focus:chromatin & epigenetic regulation· 4 Approach:experimental assay· 4 Research Focus:genome assembly· 2 Research Focus:phylogenetics / evolution· 2 Research Focus:variant calling· 2 Organism:C. elegans· 1

Frequent Co-Authors

C. Grossen· 2 shared M. Hofreiter· 2 shared M. Robin· 2 shared M. V. Westbury· 2 shared A. Barlow· 1 shared A. Byrne· 1 shared A. Ludwig· 1 shared A. M. Klittich· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersEvolutionary Biology

C. Grossen

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9 papers

Recent·Most cited

Facilitated introgression from domestic goat into Alpine ibex at immune loci

X. Muenger, M. Robin, L. Dalen, C. Grossen

The paper identifies recent introgression from domestic goats into Alpine ibex genomes, particularly at immune-related loci, suggesting adaptive benefits during population recovery.

bioRxiv · Nov 23, 2023Evolutionary Biology

Convergent evolution of skim feeding in baleen whales

L. Dutoit, K. J. Mitchell, N. Dussex, C. M. Kemper, P. Larsson, L. Dalen, N. J. Rawlence, F. G. Marx

This study sequenced the genome of pygmy right whales to resolve their evolutionary relationships and finds they are more closely related to rorquals than right whales, indicating convergent evolution of right whale-like features.

bioRxiv · Aug 16, 2022Evolutionary Biology

Blue turns to grey - Paleogenomic insights into the evolutionary history and extinction of the blue antelope (Hippotragus leucophaeus)

E. Hempel, F. Bibi, J. T. Faith, K.-P. Koepfli, A. M. Klittich, D. A. Duchene, J. S. Brink, D. C. Kalthoff, L. Dalen, M. Hofreiter, M. V. Westbury

This study recovers the first draft genomes of the extinct blue antelope, revealing its evolutionary relationships and low genetic diversity, suggesting human impact contributed to its extinction.

bioRxiv · Apr 12, 2022Evolutionary Biology

Ancient mitogenomes unravel massive genetic diversity loss during near extinction of Alpine ibex

M. Robin, G. J. Ferrari, G. Akguel, J. Von Seth, V. J. Schuenemann, L. Dalen, C. Grossen

This study uses ancient and modern mitogenomes to show a dramatic reduction in mitochondrial diversity in Alpine ibex during near extinction, with one lineage becoming dominant and another surviving in isolation.

bioRxiv · Nov 7, 2021 · PreprintEvolutionary Biology

Historical population declines prompted significant genomic erosion in the northern and southern white rhinoceros (Ceratotherium simum)

F. Sanchez Barreiro, S. Gopalakrishnan, J. Ramos-Madrigal, M. V. Westbury, M. de Manuel, A. Margaryan, M. M. Ciucani, F. G. Vieira, Y. Patramanis, D. Kalthoff, Z. Timmons, T. Sicheritz-Ponten, L. Dalen, O. A. Ryder, G. Zhang, , M. T. P. Gilbert

The paper analyzes genomic changes in white rhinoceros subspecies before and after population declines, finding reduced genetic diversity and increased inbreeding in both.

bioRxiv · May 10, 2020Evolutionary Biology

Ancient microRNA profiles of a 14,300-year-old canid are taxonomically informative and give glimpses into gene regulation from the Pleistocene

B. Fromm, M. Tarbier, O. Smith, L. Dalen, T. M. Gilbert, M. R. Friedlander

The paper analyzes ancient microRNA profiles from a 14,300-year-old canid, showing they are taxonomically informative and provide insights into Pleistocene gene regulation.

bioRxiv · Dec 16, 2019Evolutionary Biology

A roadmap to mammalian oral microbiome evolution with dental calculus

J. C. Brealey, H. G. Leitao, T. van der Valk, W. Xu, K. Bougiouri, L. Dalen, K. Guschanski

This study uses dental calculus to analyze the oral microbiome of wild mammals, revealing taxonomic, functional, and historical insights into microbiome evolution and host-pathogen interactions.

bioRxiv · Jul 4, 2019 · PreprintEvolutionary Biology

Mountain lion genomes provide insights into genetic rescue of inbred populations

N. F. Saremi, M. A. Supple, A. Byrne, J. A. Cahill, L. L. Coutinho, L. Dalen, H. V. Figueiro, W. E. Johnson, H. J. Milne, S. J. O'Brien, B. O'Connell, D. P. Onorato, S. P. Riley, J. A. Sikich, D. R. Stahler, , B. Shapiro

The paper analyzes mountain lion genomes to study genetic rescue effects in inbred populations, finding that translocated individuals quickly lose genetic diversity due to local inbreeding.

bioRxiv · Nov 29, 2018 · PreprintEvolutionary Biology

Population and conservation genomics of the world's rarest hyena species, the brown hyena (Parahyena brunnea)

M. Westbury, S. Hartmann, A. Barlow, I. Wiesel, V. Leo, R. Welch, D. M. Parker, F. Sicks, A. Ludwig, L. Dalen, M. Hofreiter

This study analyzes the population and conservation genomics of the brown hyena, revealing low genetic diversity and potential sub-populations, with implications for its conservation.

bioRxiv · Jul 31, 2017Evolutionary Biology