S. Gopalakrishnan

Ancient environmental DNA reveals the distinct fingerprints of whaling and climate change on Antarctic marine biodiversity

This study uses ancient environmental DNA to show how whaling and climate change impacted Antarctic marine biodiversity over two centuries.

Genetic differentiation in Anopheles stephensi from India and Ethiopia: insights from mitochondrial genome analysis

This study analyzes mitochondrial genomes of Anopheles stephensi from India and Ethiopia to reveal genetic differentiation and multiple lineages, suggesting independent introductions.

Imputation of ancient canid genomes reveals inbreeding history over the past 10,000 years

This study imputes ancient dog and wolf genomes to analyze inbreeding history over 10,000 years, finding lower inbreeding in ancient populations and associations between low ROH regions and olfaction/immune genes.

Fine-scale oceanographic processes shape marine biodiversity patterns in the Galapagos Islands

The paper investigates how fine-scale oceanographic processes influence marine biodiversity patterns in the Galapagos Islands using eDNA metabarcoding and ocean modeling.

Disrupted Cholesterol Biosynthesis and Hair Follicle Stem Cell Impairment in the Onset of Alopecia

This study investigates how disrupted cholesterol biosynthesis affects hair follicle stem cell function and hair follicle cycling in alopecia, finding that cholesterol inhibition leads to stem cell impairment and apoptosis.

A genomic exploration of the possible de-extirpation of the Zanzibar leopard

The paper genomically analyzes two Zanzibar leopard specimens to assess their suitability for reintroduction, finding close genetic ties to mainland East African leopards and no unique adaptive traits.

Redefining rock doves, Columba livia, using historical whole genome sequences

This study uses historical whole-genome sequences of rock doves to redefine their taxonomy, population structure, and domestication history.

Conservation implications of elucidating the Korean wolf taxonomic ambiguity through whole-genome sequencing

This study uses whole-genome sequencing to resolve the taxonomic status of the Korean wolf, finding it genetically similar to other East Asian wolves and not a distinct lineage.

Ancient DNA Reveals China as a Historical Genetic Melting Pot in Tiger Evolution

This study uses ancient DNA to trace tiger evolution, revealing China as a genetic melting pot and resolving taxonomic disputes among tiger subspecies.

Evidence of long-term purging of mutation load in killer whale genomes

The paper examines mutation load in killer whale genomes, finding that high latitude populations have fewer non-synonymous mutations, suggesting purging of recessive deleterious mutations.

Phenotypic and molecular evolution across 10,000 generations in laboratory budding yeast populations

This study tracks phenotypic and molecular evolution in 205 yeast populations over 10,000 generations, revealing patterns of declining adaptability, mutation accumulation, and genetic parallelism.

Biodiversity Soup II: A bulk-sample metabarcoding pipeline emphasizing error reduction

This paper introduces a metabarcoding pipeline to reduce errors in bulk-sample sequencing, showing reduced false positives and biases but no recovery of relative-abundance information.

Historical population declines prompted significant genomic erosion in the northern and southern white rhinoceros (Ceratotherium simum)

The paper analyzes genomic changes in white rhinoceros subspecies before and after population declines, finding reduced genetic diversity and increased inbreeding in both.

Contrasting dates of rainforest fragmentation in Africa inferred from trees with different dispersal abilities

The paper uses genetic data from five Legume tree species to infer past rainforest fragmentation in Africa, finding split dates compatible with ice-age climatic oscillations and contrasting recolonization abilities based on dispersal traits.