Intranasal Immunization with a Proteosome-Adjuvanted SARS-CoV2 Spike Protein-Based Vaccine is Immunogenic and Efficacious in Mice & Hamsters
F. C. Stark, B. Akache, L. Deschatelets, A. Tran, M. Stuible, Y. Durocher, M. J. McCluskie, G. Agbayani, R. Dudani, B. A. Harrison, T. M. Renner, S. R. Makinen, J. Bavananthasivam, D. Duque, C. D. Zarley, , J. Zimmermann
This study evaluates an intranasal vaccine formulation containing a proteosome-adjuvanted SARS-CoV-2 Spike protein, showing immunogenicity and efficacy in mice and hamsters against multiple variants.
bioRxiv · Mar 2, 2022 · PreprintImmunology