Heterologous booster with a novel formulation containing glycosylated trimeric S protein is effective againstOmicron
D. Bottero, E. Rudi, P. M. Aispuro…·D. Hozbor
This study evaluates the effectiveness of heterologous booster vaccines against Omicron BA.1 using a mouse model, showing that mRNA-based vaccines outperform vector-based ones, while heterologous boosters improve immune responses.