Author

L. Domicevica

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Biophysics· 1

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Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

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A. Cuthbert· 1 shared A. N. Kapanidis· 1 shared A. Plochowietz· 1 shared H. Kaju· 1 shared J. Hohlbein· 1 shared J. P. K. Doye· 1 shared M. Mosayebi· 1 shared M. Sustarsic· 1 shared

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1 shared paperBiophysics

A. Cuthbert

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1 paper

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BiophysicsbioRxivFeb 10, 2018

Substrate conformational dynamics drive structure-specific recognition of gapped DNA by DNA polymerase

T. D. Craggs, M. Sustarsic, A. Plochowietz…·A. N. Kapanidis

This paper investigates how DNA polymerase I recognizes gapped DNA structures through conformational dynamics, revealing a bent DNA structure and using single-molecule FRET and simulations to support the findings.

DOI 10.1093/nar/gkz797

structural biologystatistical model

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