Cancer BiologybioRxiv
Haploinsufficient tumour suppressor PRP4K is negatively regulated during epithelial-to-mesenchymal transition
L. E. Clarke, A. Cook, S. Mathavarajah…·G. Dellaire
This study shows PRP4K is a haploinsufficient tumor suppressor whose levels are reduced during EMT, promoting invasion without full EMT in mammary cells.
DOI 10.1096/fj.202001063r