Cancer BiologybioRxivPreprint
The Injury Response to DNA Damage Promotes Anti-Tumor Immunity
G. Sriram, L. E. Milling, J.-K. Chen…·M. B. Yaffe
This study shows that ex vivo DNA-damaged tumor cells as an adjuvant enhance anti-tumor immunity when combined with immune checkpoint inhibitors, requiring live injured cells and specific signaling pathways.
DOI 10.1101/2020.04.26.062216