ImmunologybioRxivPreprint
Soluble mannose receptor induces pro-inflammatory macrophage activation and metaflammation
M. Embgenbroich, H. J. van der Zande, L. Hussaarts…·S. Burgdorf
This study shows that soluble mannose receptor (sMR) promotes pro-inflammatory macrophage activation and metaflammation by inhibiting CD45 phosphatase activity, leading to metabolic dysfunctions in obesity.
DOI 10.1101/2020.09.29.315598