Author

B. Everts

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:mouse· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

B. Guigas· 4 shared A. Zawistowska-Deniziak· 3 shared F. Otto· 3 shared G. A. Heieis· 3 shared T. A. Patente· 3 shared A. Ozir-Fazalalikhan· 2 shared E. C. Brombacher· 2 shared J. M. Lambooij· 2 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

B. Guigas

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Integration of Mass Cytometry and Mass Spectrometry Imaging for Spatially Resolved Single Cell Metabolic Profiling

J. B. Nunes, M. E. Ijsselsteijn, T. Abdelaal, R. Ursem, M. van der Ploeg, B. Everts, A. Mahfouz, B. Heijs, N. de Miranda

The paper integrates mass cytometry and mass spectrometry imaging to analyze metabolic heterogeneity in tissues and its link to cell populations like cancer and immune cells.

bioRxiv · Aug 29, 2023Cancer Biology

A PD-1-ST2 axis controls Th2 effector function in tissue via a metabolic checkpoint

G. A. Heieis, B. Everts, C. W. Roberts, R. M. Maizels, G. Perona-Wright

This study shows that PD-1 signaling regulates Th2 cell metabolism and IL-33 receptor expression through fatty acid oxidation, suggesting PD-1 blockade could treat Th2-related diseases.

bioRxiv · Aug 13, 2023 · PreprintImmunology

AMPK activation induces RALDHhigh tolerogenic dendritic cells through rewiring of glucose and lipid metabolism

E. C. Brombacher, T. A. Patente, A. J. van der Ham, T. J. A. Moll, F. Otto, F. W. M. Verheijen, E. A. Zaal, A. H. de Ru, R. T. N. Tjokrodirijo, C. R. Berkers, P. A. van Veelen, B. Guigas, B. Everts

This study shows that AMPK activation makes human dendritic cells more tolerogenic by altering their metabolism, specifically increasing RALDH activity and changing lipid and glucose metabolism.

bioRxiv · Jul 4, 2023 · PreprintImmunology

Metabolic sensor AMPK licenses CD103+ dendritic cells to induce Treg responses

T. Patente, E. Brombacher, G. Heieis, L. Pelgrom, A. Zawistowska-Deniziak, F. Otto, A. Ozir-Fazalalikhan, A. van der Ham, B. Guigas, J. A. M. Barbuto, B. Everts

This study shows AMPK is essential for retinoic acid-induced CD103+ dendritic cells to promote Treg responses and control Type 2 immunity.

bioRxiv · Feb 21, 2023 · PreprintImmunology

Spectral flow cytometry reveals metabolic heterogeneity in tissue macrophages

G. A. Heieis, T. A. Patente, T. Tak, L. Almeida, B. Everts

This study uses spectral flow cytometry to reveal metabolic heterogeneity in tissue macrophages across different organs and under infection conditions.

bioRxiv · May 26, 2022Immunology

LKB1 signalling in dendritic cells controls whole-body metabolic homeostasis by limiting T helper 17 priming

H. J. P. van der Zande, E. C. Brombacher, J. M. Lambooij, L. R. Pelgrom, A. Zawistowska-Deniziak, T. A. Patente, G. A. Heieis, F. Otto, A. Ozir-Fazalalikhan, M. Yazdanbakhsh, B. Everts, B. Guigas

This study shows that LKB1 in dendritic cells limits T helper 17 cell priming, thereby protecting against obesity-induced metabolic dysfunctions.

bioRxiv · Oct 14, 2021 · PreprintImmunology

Soluble mannose receptor induces pro-inflammatory macrophage activation and metaflammation

M. Embgenbroich, H. J. van der Zande, L. Hussaarts, J. Schulte-Schrepping, L. R. Pelgrom, N. Garcia-Tardon, L. Schlautmann, I. Stoetzel, K. Handler, J. M. Lambooij, A. Zawistowska-Deniziak, L. Hoving, K. de Ruiter, M. Wijngaarden, H. Pijl, , S. Burgdorf

This study shows that soluble mannose receptor (sMR) promotes pro-inflammatory macrophage activation and metaflammation by inhibiting CD45 phosphatase activity, leading to metabolic dysfunctions in obesity.

bioRxiv · Sep 29, 2020 · PreprintImmunology