Author
L. I. Zon
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2022 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 13 mutual co-author links4 papers
Recent·Most cited
- Cell BiologybioRxivPreprint
Limb Specific Failure of Proliferation and Translation in the Mesenchyme Leads to Skeletal Defects in Diamond Blackfan Anemia
J. Hom, T. Karnavas, E. Hartman…·L. Blanc
This study identifies site-specific skeletal defects in DBA by showing limb-specific mesenchymal stem cell proliferation and translation failures linked to WNT signaling and p53.
DOI 10.1101/2022.01.14.476336 - Cancer BiologybioRxiv
SATB2 induction of a neural crest mesenchyme-like program drives invasion and drug resistance in melanoma
M. Fazio, E. van Rooijen, M. Dang…·L. I. Zon
This study shows SATB2 drives melanoma invasion and drug resistance by inducing a neural crest mesenchyme-like transcriptional program in zebrafish and human models.
- BiophysicsbioRxiv
CDK13 Mutations Drive Melanoma via Accumulation of Prematurely Terminated Transcripts
M. L. Insco, B. J. Abraham, S. J. Dubbury…·L. I. Zon
This study identifies CDK13 mutations in melanoma, showing they lead to accumulation of truncated transcripts and poor survival, with a mechanism involving impaired ZC3H14 phosphorylation and PAXT complex recruitment.