Author

L. J. Fitschen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. M. van Oijen· 1 shared A. Shirbini· 1 shared G. Tolun· 1 shared H. Yu· 1 shared J. L. Brewster· 1 shared L. M. Spenkelink· 1 shared N. Johnston· 1 shared S. H. Mueller· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

A. M. van Oijen

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2 papers

Recent·Most cited

BiochemistrybioRxivApr 9, 2022

Structure of phage lambda Red-beta(177) annealase shows how it anneals DNA strands during single-strand annealing homologous DNA recombination

T. P. Newing, J. L. Brewster, H. Yu…·G. Tolun

This paper determines the structure of Red-beta annealase using cryo-EM and proposes a mechanism for DNA strand annealing during homologous recombination.

DOI 10.1038/s41467-022-33090-6

cryo-EMexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivMar 3, 2022

Rapid single-molecule characterisation of nucleic-acid enzymes

S. H. Mueller, L. J. Fitschen, A. Shirbini…·A. M. van Oijen

This paper introduces a single-molecule assay to rapidly characterize DNA metabolism enzymes by measuring fluorescence intensity changes during DNA synthesis, unwinding, or digestion.

DOI 10.1093/nar/gkac949

E. coliDNA methylation

𝕏 PostBluesky