PhysiologybioRxiv
The mitochondrial Ca2+ uniporter MCU is required for normal glucose-stimulated insulin secretion in vitro and in vivo
E. Haythorne, E. Georgiadou, M. Dickerson…·G. A. Rutter
This study shows that the mitochondrial Ca2+ uniporter MCU is essential for normal glucose-stimulated insulin secretion in pancreatic beta-cells, both in vitro and in vivo.
DOI 10.1007/s00125-020-05148-x