Author

L. M. Guenther

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

A. Kasumova· 1 shared B. S. Justis· 1 shared C. Taslim· 1 shared E. J. P. Tokarsky· 1 shared E. R. Theisen· 1 shared G. Alexe· 1 shared G. Rask· 1 shared J. C. Crow· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperCancer Biology

A. Kasumova

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1 paper

Recent·Most cited

Cancer BiologybioRxivDec 13, 2021

Mitochondrial Dysfunction is a Driver for SP-2509 Drug Resistance in Ewing Sarcoma

E. J. P. Tokarsky, J. C. Crow, L. M. Guenther…·E. R. Theisen

The paper identifies mitochondrial dysfunction as a mechanism of resistance to the LSD1 inhibitor SP-2509 in Ewing sarcoma and suggests combining LSD1 inhibitors with mitochondrial-targeting agents.

DOI 10.1158/1541-7786.mcr-22-0027

humanbulk RNA-seq

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