Author

G. Rask

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

A. Kasumova· 1 shared B. S. Justis· 1 shared C. Taslim· 1 shared E. J. P. Tokarsky· 1 shared E. R. Theisen· 1 shared F. Warnberg· 1 shared G. Alexe· 1 shared G. Martinez-Nieto· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Kasumova

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Collagen XVIII promotes breast cancer through EGFR/ErbB signaling and its ablation improves the efficacy of ErbB-targeting inhibitors

R. Devarajan, H. Peltoketo, V. Izzi, H. J. Ruotsalainen, S. Kauppila, M.-R. Vaisanen, G. Rask, G. Martinez-Nieto, S.-M. Karppinen, T. Vaisanen, I. Kaur, J. P. Koivunen, T. Sasaki, R. Winqvist, F. Warnberg, , R. Heljasvaara

This study shows that collagen XVIII promotes breast cancer via EGFR/ErbB signaling and sustains cancer stem cells, and its inhibition enhances the effectiveness of ErbB-targeting therapies.

bioRxiv · Jan 10, 2022 · PreprintCancer Biology

Mitochondrial Dysfunction is a Driver for SP-2509 Drug Resistance in Ewing Sarcoma

E. J. P. Tokarsky, J. C. Crow, L. M. Guenther, J. Sherman, C. Taslim, G. Alexe, K. I. Pishas, G. Rask, B. S. Justis, A. Kasumova, K. Stegmaier, S. L. Lessnick, E. R. Theisen

The paper identifies mitochondrial dysfunction as a mechanism of resistance to the LSD1 inhibitor SP-2509 in Ewing sarcoma and suggests combining LSD1 inhibitors with mitochondrial-targeting agents.

bioRxiv · Dec 13, 2021Cancer Biology