Cancer BiologyNeuro-OncologyPeer-reviewed
Cancer-associated SMARCAL1 loss-of-function mutations promote alternative lengthening of telomeres and tumorigenesis in telomerase-negative glioblastoma cells
H. Liu, C. Xu, B. H. Diplas…·M. S. Waitkus
This study shows SMARCAL1 loss-of-function mutations enable ALT in telomerase-negative glioblastoma cells, promoting tumorigenesis and telomere maintenance.
DOI 10.1093/neuonc/noad022