Cancer BiologybioRxivPreprint
Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics
A. Koessinger, D. Koessinger, K. Kinch…·S. Tait
This study shows that glioblastoma (GBM) is highly sensitive to BH3-mimetics due to elevated anti-apoptotic BCL-xL and MCL-1 expression, which can be therapeutically targeted.
DOI 10.1101/2021.06.13.448232