Author

F. Bock

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

R. Zent· 2 shared A. J. Chalmers· 1 shared A. Koessinger· 1 shared A. S. Terker· 1 shared A. Simonis· 1 shared A. X. Miranda· 1 shared B. A. Bailey-Elkin· 1 shared B. Brachvogel· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

R. Zent

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Alveolar repair following lipopolysaccharide-induced injury requires cell-extracellular matrix interactions

J. M. S. Sucre, F. Bock, N. M. Negretti, J. T. Benjamin, P. M. Gulleman, X. Dong, K. T. Ferguson, C. S. Jetter, W. Han, Y. Liu, S. Kook, J. Gokey, S. H. Guttentag, J. A. Kropski, T. S. Blackwell, , E. J. Plosa

This study shows that β1-containing integrins are essential for alveolar repair after injury, as their absence leads to emphysema and impaired differentiation of AT2 cells into mature type 1 alveolar epithelial cells.

bioRxiv · Aug 5, 2022 · PreprintCell Biology

The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm

M. Hamdorf, T. Imhof, B. A. Bailey-Elkin, J. Betz, S. J. Theobald, A. Simonis, V. Di Cristanziano, L. Gieselmann, F. Dewald, C. Lehmann, M. Augustin, F. Klein, M. A. Alcazar, R. Rogisch, M. Fabri, , F. Bock

This study shows that SARS-CoV-2's ORF8 protein binds to human dendritic cells, induces cytokine storms, and may be a target for therapeutic intervention.

bioRxiv · Jun 6, 2022 · PreprintImmunology

Kidney collecting duct cells make vasopressin in response to NaCl induced hypertonicity

J. P. Arroyo, A. S. Terker, Y. Zuchowski, J. A. Watts, F. Bock, C. Meyer, W. Luo, M. E. Kapp, E. R. Gould, M. Jiang, A. X. Miranda, M. Jiang, R. Vanacore, E. Hammock, M. Wilson, , R. C. Harris

The paper shows that mouse and human kidneys produce biologically active vasopressin in response to NaCl-induced hypertonicity and water restriction.

bioRxiv · May 13, 2022Physiology

Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics

A. Koessinger, D. Koessinger, K. Kinch, L. Martinez-Escardo, N. Paul, Y. Elmasry, G. Malviya, C. Cloix, K. Campbell, F. Bock, J. O'Prey, K. Stevenson, C. Nixon, M. Jackson, G. Ichim, , S. Tait

This study shows that glioblastoma (GBM) is highly sensitive to BH3-mimetics due to elevated anti-apoptotic BCL-xL and MCL-1 expression, which can be therapeutically targeted.

bioRxiv · Jun 13, 2021 · PreprintCancer Biology