Author

L. Murin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

A. Scasny· 2 shared B. Alibayov· 2 shared J. E. Vidal· 2 shared A. G. Jop Vidal· 1 shared A. G. Vidal· 1 shared B. Jackson· 1 shared F. Khan· 1 shared K. Beaton· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

A. Scasny

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Heme-Mediated Selection of Encapsulated Streptococcus pneumoniae in the Lungs by Oxidative Stress

B. Alibayov, A. G. Jop Vidal, L. Murin, A. Scasny, K. Takeshita, K. Beaton, K. Edwards, T. Punshon, B. Jackson, L. S. McDaniel, J. E. Vidal

This study shows that heme from oxidized hemoglobin promotes the selection of encapsulated Streptococcus pneumoniae in the lungs, linking oxidative stress to pneumococcal pneumonia pathogenesis.

bioRxiv · Nov 14, 2023Microbiology

Oxidation of hemoproteins by Streptococcus pneumoniae collapses the cell cytoskeleton and disrupts mitochondrial respiration leading to cytotoxicity of human lung cells

A. Scasny, B. Alibayov, F. Khan, S. Rao, L. Murin, A. G. Vidal, P. Smith, L. Wei, K. S. Edwards, K. Warncke, J. E. Vidal

This study shows that Streptococcus pneumoniae produces H2O2, which oxidizes hemoproteins like hemoglobin and cytochrome c, leading to mitochondrial dysfunction and cell death in human lung cells.

bioRxiv · Jun 7, 2023 · PreprintMicrobiology