K. Edwards

Heme-Mediated Selection of Encapsulated Streptococcus pneumoniae in the Lungs by Oxidative Stress

This study shows that heme from oxidized hemoglobin promotes the selection of encapsulated Streptococcus pneumoniae in the lungs, linking oxidative stress to pneumococcal pneumonia pathogenesis.

A genome-wide overexpression screen reveals Mycobacterium smegmatis growth inhibitors encoded by mycobacteriophage Hammy

The paper identifies 24 gene products from Mycobacteriophage Hammy that inhibit Mycobacterium smegmatis growth through a genome-wide overexpression screen.

HIV-1 resistance to islatravir/tenofovir combination therapy in wild-type or NRTI resistant strains of diverse HIV-1 subtypes

This study evaluates resistance to islatravir and tenofovir in HIV-1 strains with mutations K65R, M184V, and S68G/N, showing that their combination has a high genetic barrier to resistance.

Widespread reductions in body size are paired with stable assemblage biomass.

The paper assesses body size changes across six taxon groups and finds that decreases in body size are paired with stable assemblage biomass due to compensatory abundance increases.

ADO-MEDIATED SYNTHESIS OF TAURINE ALTERS THE CHROMATIN LANDSCAPE OF INGUINAL ADIPOSE TISSUE TO ENHANCE NON-SHIVERING THERMOGENESIS

This study shows taurine biosynthesis via ADO enhances NST in inguinal adipose tissue by remodeling chromatin to increase gene transcription for thermogenesis.

A simple method for spray-on gene editing in planta.

This paper introduces a simple, inexpensive, and fast method for spray-on gene editing in multiple crop species using carbon dots to deliver plasmids.

Host traits drive viral life histories across phytoplankton viruses

The paper examines how host traits influence viral life history traits in phytoplankton viruses, finding host genome size and growth rate explain 40-50% of variation in burst size and latent period.