Author

L. N. Scott

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

M. G. Lechner· 2 shared W. HUGO· 2 shared A. Drakaki· 1 shared A. Ribas· 1 shared A. T. Hoang· 1 shared A. Y. Patel· 1 shared H.-C. Chen· 1 shared J. Ortega· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

M. G. Lechner

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyFrontiers in ImmunologyPeer-reviewedJun 26, 2023

Antigen presentation by clonally diverse CXCR5+ B cells to CD4 and CD8 T cells is associated with durable response to immune checkpoint inhibitors.

L. Ding, L. Sun, M. T. Bu…·W. HUGO

This study identifies that clonally diverse CXCR5+ B cells enhance IFNγ pathway activity and CD8 T cell responses, leading to durable ICI therapy outcomes in melanoma.

DOI 10.3389/fimmu.2023.1176994

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintDec 18, 2022

Clonally-Expanded, Thyrotoxic Autoimmune Mediator CD8+ T cells Driven by IL21 Contribute to Checkpoint Inhibitor Thyroiditis

M. G. Lechner, Z. Zhou, A. T. Hoang…·M. A. Su

The paper identifies clonally expanded CD8+ T cells driven by IL21 in ICI-thyroiditis using scRNA-seq and validates their role in thyroid inflammation.

DOI 10.1101/2022.12.18.517398

humanscRNA-seq

𝕏 PostBluesky