Author

L. S. Hancox

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Immunology· 1

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

B. Poudel· 1 shared C. Marques-da-Silva· 1 shared D. E. Kyle· 1 shared J. C. Shiau· 1 shared J. T. Harty· 1 shared K. Peissig· 1 shared L. Pewe· 1 shared M. J. Shears· 1 shared

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2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

B. Poudel

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintJan 28, 2021

Altered cleavage of Caspase-1 in hepatocytes limits control of malaria in the liver

C. Marques-da-Silva, B. Poudel, R. P. Baptista…·S. P. Kurup

This study shows that limited Caspase-1 cleavage in hepatocytes reduces pyroptosis and cytokine maturation, impairing malaria control, and that enhancing ASC expression improves immune response.

DOI 10.1101/2021.01.28.427517

mousebulk RNA-seq

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