Author

L. Sunuwar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1

Frequent Co-Authors

J. Yin· 2 shared k. karalis· 2 shared M. Donowitz· 2 shared m. Kasendra· 2 shared A. Apostolou· 1 shared A. Wildeman· 1 shared D. V. Manatakis· 1 shared G. A. Hamilton· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

J. Yin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Hepatobiliary manganese homeostasis is dynamic in the setting of illness in mice

L. Sunuwar, V. Tomar, A. Wildeman, V. Culotta, J. M. Melia

This paper shows that systemic manganese homeostasis changes dynamically in mice during illness, with altered liver and biliary manganese levels in response to infection and colitis.

bioRxiv · Mar 22, 2023Physiology

Mechanical Stimuli Affect E. coli Heat Stable Enterotoxin-cyclic GMP Signaling in a Human Enteroid Intestine-Chip Diarrhea Model

l. sunuwar, J. Yin, m. Kasendra, k. karalis, J. Kaper, J. M. Fleckenstein, M. Donowitz

This study shows that fluid flow in an Intestine-Chip model alters intestinal epithelial responses to E. coli heat-stable enterotoxin, increasing cGMP secretion without enhancing intracellular cGMP.

bioRxiv · Sep 18, 2019Microbiology

Organoid-derived Duodenum Intestine-Chip for preclinical drug assessment in a human relevant system

M. Kasendra, R. Luc, J. Yin, D. V. Manatakis, A. Apostolou, L. Sunuwar, J. Obrigewitch, G. A. Hamilton, M. Donowitz, K. Karalis

The paper develops a human Duodenum Intestine-Chip model to better predict drug metabolism and drug-drug interactions by emulating intestinal functions and CYP450 induction.

bioRxiv · Aug 5, 2019Cell Biology