Author

L. Sussel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Lietzke· 1 shared A. M. Stendahl· 1 shared A. Renberg· 1 shared B. A. Kaufman· 1 shared B. Thompson· 1 shared C. Deiter· 1 shared C. Nicora· 1 shared D. L. Hubers· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. Lietzke

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2 papers

Recent·Most cited

Reduction of chemokine CXCL9 expression by omega-3 fatty acids via ADP-ribosylhydrolase ARH3 in MIN6 insulin-producing cells

Y. You, S. Sarkar, C. Deiter, E. Elliott, C. Nicora, R. Mirmira, L. Sussel, E. Nakayasu

This study shows omega-3 fatty acids reduce CXCL9 expression in MIN6 cells via ARH3, potentially protecting beta cells from immune attack and preventing T1D.

bioRxiv · Jan 30, 2024Cell Biology

Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues

G. L. Pearson, E. M. Walker, N. Lawlor, A. Lietzke, V. Sidarala, J. Zhu, T. Stromer, E. C. Reck, A. M. Stendahl, J. Li, E. Levi-D'Ancona, M. B. Pasmooij, D. L. Hubers, A. Renberg, K. Mohamed, , S. A. Soleimanpour

This study shows that mitochondrial dysfunction triggers a retrograde signaling program that reduces cellular maturity in metabolic tissues, and blocking this signaling can restore cell identity and improve hyperglycemia.

bioRxiv · Aug 2, 2022 · PreprintCell Biology