BiochemistrybioRxiv
Evolutionary trajectory of receptor binding specificity and promiscuity of the spike protein of SARS-CoV-2
C. Planchais, A. Reyes-Ruiz, R. Lacombe…·J. D. Dimitrov
The paper investigates how the SARS-CoV-2 spike protein's interaction with ACE2 evolved, revealing changes in binding dynamics and physicochemical forces across variants.
DOI 10.1002/pro.4447