Author

L. Trusolino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:clinical cohort / trial· 1

Frequent Co-Authors

A. Bertotti· 2 shared A. Bardelli· 1 shared A. Bartolini· 1 shared A. D. Campbell· 1 shared A. Easton· 1 shared A. Ferrero· 1 shared A. K. Najumudeen· 1 shared A. Lorenzato· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

A. Bertotti

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3 papers

Recent·Most cited

Cancer BiologybioRxivJul 10, 2023

XENTURION, a multidimensional resource of xenografts and tumoroids from metastatic colorectal cancer patients for population-level translational oncology

S. M. Leto, E. Grassi, M. Avolio…·L. Trusolino

XENTURION provides a resource of PDX models and tumoroids from metastatic CRC patients, revealing variable cetuximab responses and identifying therapeutic targets through cross-platform validation.

DOI 10.1038/s41467-024-51909-2

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivJun 11, 2022

Molecular phenotyping of colorectal neoplasia shows dynamic and adaptive cancer stem cell population admixture

E. Gil Vazquez, N. Nasreddin, G. N. Valbuena…·S. J. Leedham

The paper examines stem cell population dynamics in colorectal tumors, showing that CBC-RSC admixture correlates with mutations and microenvironmental changes, and is linked to chemoresistance.

DOI 10.1016/j.stem.2022.07.008

mousehuman

𝕏 PostBluesky

Cancer BiologybioRxivJun 11, 2019

Evolving neoantigen profiles in colorectal cancers with DNA repair defects

G. Rospo, A. Lorenzato, N. Amirouchene-Angelozzi…·A. Bardelli

This study tracks neoantigen profiles in colorectal cancers with DNA repair defects, finding dynamic patterns linked to antigen presentation downregulation and evolvability.

DOI 10.1186/s13073-019-0654-6

humanwhole-exome sequencing

𝕏 PostBluesky