ImmunologybioRxivPreprint
Therapeutic blockade of Activin-A improves NK cell function and anti-tumor immunity
Jai Rautela, Laura F. Dagley, Iona S. Schuster…·Fernando Souza-Fonseca-Guimaraes
This study shows Activin-A inhibits NK cell function, promotes transdifferentiation into ILC1-like cells, and suppresses anti-tumor immunity, with therapeutic blockade improving outcomes.