Cancer BiologyEuropean Journal of CancerPeer-reviewed
HER2 overexpression initiates breast tumorigenesis non-cell-autonomously by inducing oxidative stress in the tissue microenvironment
Sevim Beyza Gürler, Oliver Wagstaff, Lili Dimitrova…·Ahmet Uçar
This study shows HER2 overexpression drives breast tumorigenesis by inducing oxidative stress in the tissue microenvironment, not directly in cancer stem cells.