Author

Lina G. Abdelmoti

University of Kentucky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Emilia GalperiniD· 2 shared Daileen Landestoy· 1 shared Eric Christian RouchkaiD· 1 shared Kalina AndreevaiD· 1 shared Olivia Tussey· 1 shared Patricia G. Wilson· 1 shared Rebecca G. NorcrossiD· 1 shared Tianyan GaoiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

Emilia GalperinORCID

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2 papers

Recent·Most cited

BiochemistryHuman Molecular GeneticsPeer-reviewedJun 10, 2024

The expression of congenital Shoc2 variants induces AKT-dependent feedback activation of the ERK1/2 pathway

Patricia G. Wilson, Lina G. Abdelmoti, Tianyan Gao, Emilia Galperin

This study shows that Shoc2 variants associated with NSLH alter ERK1/2 phosphorylation levels depending on AKT pathway activation, revealing a feedback mechanism in EGFR signaling.

1 citation

humanexperimental assay

𝕏 PostBluesky

Developmental BiologyDevelopmental BiologyPeer-reviewedOct 18, 2022

Shoc2 controls ERK1/2-driven neural crest development by balancing components of the extracellular matrix

Rebecca G. Norcross, Lina G. Abdelmoti, Eric Christian Rouchka…·Emilia Galperin

This study shows that Shoc2 regulates neural crest development by modulating extracellular matrix gene expression and that its loss causes ECM imbalance linked to NSLH.

9 citations

zebrafishbulk RNA-seq

𝕏 PostBluesky