Emilia Galperin

The paper identifies PYCR1 as an interacting protein of IDE, showing that their interaction modulates IDE activity and may regulate mitochondrial IDE function.

This study identifies Shoc2 as a critical regulator of lymphangiogenesis by suppressing mTORC1-mediated IFN responses, leading to lymphatic vasculature loss and cellular senescence.

This study shows that Shoc2 variants associated with NSLH alter ERK1/2 phosphorylation levels depending on AKT pathway activation, revealing a feedback mechanism in EGFR signaling.

This study shows that Shoc2 regulates neural crest development by modulating extracellular matrix gene expression and that its loss causes ECM imbalance linked to NSLH.