BiochemistrybioRxiv
High-throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain
M. A. Dasovich, J. Zhuo, A. G. Thomas…·A. Leung
The paper develops a high-throughput assay for screening inhibitors of the SARS-CoV-2 Mac1 macrodomain and identifies dasatinib and dihydralazine as inhibitors with selectivity over human MacroD2.
DOI 10.1021/acschembio.1c00721