PhysiologybioRxiv
MFGE8 links absorption of dietary fatty acids with catabolism of enterocyte lipid stores through HNF4 γ- dependent transcription of CES enzymes
R. Datta, M. A. Gholampour, C. D. Yang…·K. Atabai
This study identifies CES1D as the hydrolase downstream of the MFGE8-vβ5 integrin pathway that regulates catabolism of diet-derived lipid droplets in enterocytes.
DOI 10.1016/j.celrep.2023.112249