Author

M. A. Simon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Assay:electrophysiology· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

L. Csanady· 2 shared A. Szollosi· 1 shared B. Mag· 1 shared D. Sharifi Kia· 1 shared E. A. Goncharova· 1 shared E. Bartus· 1 shared E. Boros· 1 shared G. Gogl· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiophysics

L. Csanady

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein

M. A. Simon, I. Iordanov, A. Szollosi, L. Csanady

The paper estimates the non-hydrolytic closing rate of WT CFTR by comparing it to mutants with disrupted ATP hydrolysis, revealing how specific mutations affect this rate.

bioRxiv · Jul 16, 2023Biophysics

Molecular pathology of a cystic fibrosis mutation is explained by loss of a hydrogen bond

M. A. Simon, L. Csanady

The paper identifies a hydrogen bond critical for CFTR gating and shows its loss explains the gating defect in the R117H mutation.

bioRxiv · Oct 19, 2021Biophysics

Binding Profile Mapping of the S100 Protein Family Using a High-throughput Local Surface Mimetic Holdup Assay

M. A. Simon, E. Bartus, B. Mag, E. Boros, L. Roszjar, G. Gogl, G. Trave, T. A. Martinek, L. Nyitray

This study maps the binding promiscuity of S100 proteins using a high-throughput assay against a library of foldamers, providing insights for drug design.

bioRxiv · Dec 2, 2020 · PreprintBiochemistry

Effects of Healthy Aging on Right Ventricular Structure and Biomechanical Properties

D. Sharifi Kia, Y. Shen, T. N. Bachman, E. A. Goncharova, K. Kim, M. A. Simon

This study examines how healthy aging affects right ventricular structure and biomechanical properties in rats, finding increased peak pressures, wall thickness, and fiber reorientation.

bioRxiv · Sep 8, 2020 · PreprintBioengineering