MicrobiologybioRxiv
Targeting the Annexin A1-FPR2/ALX pathway for host-directed therapy in dengue disease
V. V. Costa, M. A. Sugimoto, J. Hubner…·M. M. Teixeira
This study identifies reduced Annexin A1 levels in dengue patients and mice, showing that AnxA1 agonists reduce disease severity by modulating mast cell degranulation.
DOI 10.7554/elife.73853