BioengineeringbioRxiv
A biomimetic five-module chimeric antigen receptor (5MCAR) designed to target and eliminate antigen-specific T cells
S. Kobayashi, M. A. Thelin, H. L. Parrish…·M. S. Kuhns
This paper designs a biomimetic 5MCAR to target and eliminate antigen-specific T cells, showing it can mitigate type I diabetes in NOD mice.
DOI 10.1073/pnas.2012495117