Author

M. Akbari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Seyfoori· 2 shared M. Amereh· 2 shared P. Walter· 2 shared S. Shojaei· 2 shared A. Ravandi· 1 shared A. Srivastava· 1 shared C. Clark· 1 shared C. Pasco· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

A. Seyfoori

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tumoroid-on-a-Plate (ToP): Physiologically Relevant Cancer Model Generation and Therapeutic Screening

A. Seyfoori, K. Liu, H. Caruncho, P. Walter, M. Akbari

This study introduces a 3D tumor model called ToP for generating predictive cancer models and screening therapeutics for glioblastoma and pancreatic adenocarcinoma.

bioRxiv · Apr 15, 2024Bioengineering

Metabolic Vulnerabilities of Temozolomide-Resistant Glioblastoma Cells: Implications for Targeted Therapies and Overcoming Chemoresistance

M. Amereh, A. Seyfoori, S. Shojaei, S. Lane, T. Zhao, M. Shokrollahi, J. Lum, P. Walter, M. Akbari

The paper identifies metabolic vulnerabilities in TMZ-resistant glioblastoma cells, showing that iron reduction enhances the efficacy of TMZ through mechanisms involving Hif1, autophagy, and ROS.

bioRxiv · Mar 1, 2024 · PreprintCancer Biology

A multi-omics analysis of glioma chemoresistance using a hybrid microphysiological model of glioblastoma

S. Shojaei, J. Basso, M. Amereh, J. Alizadeh, T. Dehesh, S. D. S. Rosa, C. Clark, M. Hassan, M. Tomczyk, L. Cole, G. Hatch, V. Dolinsky, C. Pasco, D. Schibli, S. Dhingra, , M. Akbari

This study uses a hybrid microphysiological model to analyze glioma chemoresistance and identifies molecular changes associated with resistance mechanisms.

bioRxiv · Oct 29, 2022 · PreprintBioengineering