A. Ravandi

A Lipidomics Approach to Determine the Role of Lipids and its Crosstalk with Autophagy in Lung Cancer Metastasis

The paper uses lipidomics to investigate the role of lipids and their interaction with autophagy in lung cancer metastasis.

Valvular Prostaglandins are Elevated in Severe Human Aortic Valve Stenosis

The paper identifies elevated valvular prostaglandins in severe aortic valve stenosis, linking them to disease severity and suggesting COX inhibition as a potential therapeutic target.

A multi-omics analysis of glioma chemoresistance using a hybrid microphysiological model of glioblastoma

This study uses a hybrid microphysiological model to analyze glioma chemoresistance and identifies molecular changes associated with resistance mechanisms.

Oxidised phosphatidylcholines induce multiple functional defects in airway epithelial cells

This study shows oxidized phosphatidylcholines (OxPC) impair airway epithelial cell function, causing barrier dysfunction, reduced proliferation, and oxidative stress, consistent with asthma pathology.

Reversible Mitochondrial Fragmentation in iPSC-Derived Cardiomyocytes from Children with DCMA, a Mitochondrial Cardiomyopathy

This study uses iPSC-derived cardiomyocytes from DCMA patients to show reversible mitochondrial fragmentation and OPA1 isoform imbalance, suggesting SS-31 as a potential therapy.

SS-31 Reverses Mitochondrial Fragmentation in Fibroblasts from Patients with DCMA, a Mitochondrial Cardiomyopathy

This study shows that SS-31 reverses mitochondrial fragmentation and increases ROS in DCMA fibroblasts, suggesting it as a potential therapy for this mitochondrial cardiomyopathy.