ImmunologybioRxivPreprint
Mucosal immune stimulation with HSV-2 and polyICLC boosts control of viremia in SIVΔNef vaccinated rhesus macaques with breakthrough SIV infection
M. Aravantinou, O. Mizenina, T. Brill…·N. Derby
This study investigates how HSV-2 and polyICLC immune stimulation affects SIV vaccine efficacy in rhesus macaques, finding that mucosal immune activation can enhance control of viremia in breakthrough infections.
DOI 10.1101/2020.06.02.129494