Controllable self-replicating RNA vaccine delivered intradermally elicits predominantly cellular immunity
T. Amano, H. Yu, M. Amano, E. Leyder, M. Badiola, P. Ray, J. Kim, A. C. Ko, A. Achour, N.-p. Weng, E. Kochba, Y. Levin, M. S. H. Ko
This paper develops a temperature-controlled self-replicating RNA vaccine that elicits cellular immunity and can be used as a pan-coronavirus booster.
bioRxiv · Sep 5, 2022Immunology