M. Bastmeyer

Modelling Cell Shape in 3D Structured Environments: A Quantitative Comparison with Experiments

This paper compares different computational models for predicting 3D cell shapes in structured environments with experimental data, finding that a linear area energy Hamiltonian performs best.

S100A11 promotes focal adhesion disassembly via myosin II-driven contractility and Piezo1-mediated Ca2+ entry

This study identifies S100A11's role in promoting focal adhesion disassembly through myosin II-driven contractility and Piezo1-mediated Ca2+ entry.

Nonmuscle myosin IIA dynamically guides regulatory light chain phosphorylation and assembly of nonmuscle myosin IIB

The paper investigates the dynamic roles of nonmuscle myosin IIA and IIB in regulating minifilament assembly and force generation through phosphorylation and co-assembly mechanisms.

Distinct roles of nonmuscle myosin II isoforms for establishing tension and elasticity during cell morphogenesis

This study investigates the distinct roles of nonmuscle myosin II isoforms in cell morphogenesis by analyzing their contributions to tension and elasticity using CRISPR/Cas9 knockouts and mathematical modeling.

Phosphorylated paxillin and FAK constitute subregions within focal adhesions

The paper uses super-resolution microscopy to show that phosphorylated paxillin and FAK form spatially defined clusters within focal adhesions, which are mechanosensitive and dynamic.

Ligand binding promiscuity of αVβ3 integrin is enlarged in response to mechanical force

This study shows that mechanical force increases the ligand promiscuity of αVβ3 integrin by enabling binding to fibronectin through conformational changes.