BiochemistrybioRxiv
Tubular Mitochondrial Pyruvate Carrier Disruption Elicits Redox Adaptations that Protect from Acute Kidney Injury
A. Rauckhorst, G. V. Martinez, G. M. Andrade…·D. Zepeda-Orozco
The paper shows that reducing mitochondrial pyruvate carrier activity in kidney tubular cells protects against acute kidney injury by enhancing redox defenses and survival.
DOI 10.1016/j.molmet.2023.101849